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Protein Analysis

This workbook allows the analysis of sample or imported protein sequences. The model can analyze protein sequences up to 500 amino acids long. The program analyzes five aspects of the protein sequence: the highest potential charge along the protein sequence, the amino acid composition of the protein sequence, the isoelectric point of the protein sequence at varying pHs, the hydrophobicity to predict surface and membrane spanning regions of the protein sequence and the protein structure using the Chau and Fassman algorithm.


John R. Jungck, Beloit College
Annelise L Myers, Beloit College
Srebrenka Robic, Agnes Scott College
Gerry Shaw, University of Florida - Gainesville

Published by: BioQUEST Curriculum Consortium

OS: all

User Manuals and Curricular Materials
Popular Text Citations

“Protein Hydrophobicity Plots”. (1998) Colorado State University. Accessed 30 June 2005

King, M.W., 2005. IU School of Medicine.

White, S. (2002) “Experimentally determined hydrophobicity scales”. From The Stephen White Laboratory at UC Irvine. Accessed 1 July 2005.

Research Articles

Hopp, T.P.; Woods, K.R. (1981) Prediction of protein antigenic determinants from amino acid sequences. Immunology, 78:3824-3828.

Jungck, J.R. (1978) The Genetic Code as a Periodic Table. Journal of Molecular Evolution, 11: 211-224.

Education Research & Pedagogical Materials

Shaw, G., (1998). 'Spreadsheets in Molecular Biology'. In Spreadsheets in Science and Engineering. Springer-Verlag, Berlin, Pages 203-228.

Shaw, G., (1995). Protein sequence interpretation using a spreadsheet program. BioTechniques, Volume 19, Pages 978-983.

Jungck John R., Myers Annelise L, Robic Srebrenka , Shaw Gerry () Protein Analysis. A module of the Biological ESTEEM Collection, published by the BioQUEST Curriculum Consortium. URL: