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Globin Gene Server
A database of sequences alignments and experimental results fro the beta-like gene cluster of mammals.
This site provides data and tools for studying the function of DNA sequences, with an emphasis on those involved in the production of hemoglobin. It includes information about naturally-occurring human hemoglobin mutations and their effects, experimental data related to the regulation of the beta-like globin gene cluster, and software tools for comparing sequences with one another to discover regions that are likely to play significant roles.
See the following for more info:
Globin PowerPoint by Sam Donovan
set of tools for finding conserved regions in alignments
Molecule of the month at PDB
Globin Gene Labs
http://pir.georgetown.edu/ (Search for Globin)
Bashford, D., Chothia, C., and Lesk, A. M. (1987). Determinants of a protein fold: Unique features of the globin bamino acid sequences. J. Mol. Biol., 196:199-216.
Hardison, Ross. Hemoglobins from Bacteria to Man: Evolution of
Different Patterns of Gene Expression.